Kinetex 2.6 μm PS C18 Core-Shell Column’s Chromatographic Performance and Unique Reversed Phase Selectivity in Comparison to a Conventional Fully Porous UHPLC Column

Abstract:

In this application, we investigated the Kinetex 2.6 μm PS C18 HPLC/UHPLC column’s improved chromatographic performance and unique multi-interaction selectivity when applied to a screen of 36 tricyclic antidepressants (TCA). Because the Kinetex 2.6 μm core-shell (superficially porous) particle morphology provides ultra- high column efficiency on any HPLC or UHPLC system1, the investigation also included a comparison to a conventual fully porous 1.9 μm UHPLC column.

Document Type:

Technical Notes

Industries:

Pharmaceutical/Biopharmaceutical

Techniques:

HPLC / UHPLC

Brands:

Kinetex

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